Assay
Age
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Immunohistochemistry (section)
13.5 DPC
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Smad2 SMAD family member 2 (Synonyms: 7120426M23Rik, Madh2, Madr2, Smad 2) | |
Results | Reference |
1 | J:157018 Alarcon C, Zaromytidou AI, Xi Q, Gao S, Yu J, Fujisawa S, Barlas A, Miller AN, Manova-Todorova K, Macias MJ, Sapkota G, Pan D, Massague J, Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways. Cell. 2009 Nov 13;139(4):757-69 |
1 | J:157112 Bjork BC, Turbe-Doan A, Prysak M, Herron BJ, Beier DR, Prdm16 is required for normal palatogenesis in mice. Hum Mol Genet. 2010 Mar 1;19(5):774-89 |
1 | J:101677 Butts SC, Liu W, Li G, Frenz DA, Transforming growth factor-beta1 signaling participates in the physiological and pathological regulation of mouse inner ear development by all-trans retinoic acid. Birth Defects Res A Clin Mol Teratol. 2005 Apr;73(4):218-28 |
1 | J:182705 Choe Y, Siegenthaler JA, Pleasure SJ, A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron. 2012 Feb 23;73(4):698-712 |
1 | J:332217 Feng J, Han X, Yuan Y, Cho CK, Janeckova E, Guo T, Pareek S, Rahman MS, Zheng B, Bi J, Jing J, Zhang M, Xu J, Ho TV, Chai Y, TGF-beta signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development. Elife. 2022 Dec 21;11 |
1 | J:184924 Fernandes M, Antoine M, Hebert JM, SMAD4 is essential for generating subtypes of neurons during cerebellar development. Dev Biol. 2012 May 1;365(1):82-90 |
1 | J:114987 Ge G, Greenspan DS, BMP1 controls TGFbeta1 activation via cleavage of latent TGFbeta-binding protein. J Cell Biol. 2006 Oct 9;175(1):111-20 |
1* | J:244781 Glover JD, Wells KL, Matthaus F, Painter KJ, Ho W, Riddell J, Johansson JA, Ford MJ, Jahoda CAB, Klika V, Mort RL, Headon DJ, Hierarchical patterning modes orchestrate hair follicle morphogenesis. PLoS Biol. 2017 Jul;15(7):e2002117 |
1* | J:218065 Hayata T, Yoichi, Ezura, Asashima M, Nishinakamura R, Noda M, Dullard/Ctdnep1 Regulates Endochondral Ossification via Suppression of TGF-beta Signaling. J Bone Miner Res. 2015 Feb;30(2):318-29 |
1 | J:152572 Iwao K, Inatani M, Matsumoto Y, Ogata-Iwao M, Takihara Y, Irie F, Yamaguchi Y, Okinami S, Tanihara H, Heparan sulfate deficiency leads to Peters anomaly in mice by disturbing neural crest TGF-beta2 signaling. J Clin Invest. 2009 Jul;119(7):1997-2008 |
1 | J:179089 Jaffe M, Sesti C, Washington IM, Du L, Dronadula N, Chin MT, Stolz DB, Davis EC, Dichek DA, Transforming Growth Factor-beta Signaling in Myogenic Cells Regulates Vascular Morphogenesis, Differentiation, and Matrix Synthesis. Arterioscler Thromb Vasc Biol. 2012 Jan;32(1):e1-e11 |
1 | J:204229 Li L, Wang Y, Lin M, Yuan G, Yang G, Zheng Y, Chen Y, Augmented BMPRIA-mediated BMP signaling in cranial neural crest lineage leads to cleft palate formation and delayed tooth differentiation. PLoS One. 2013;8(6):e66107 |
1* | J:257228 Li S, Pan Y, Differential expression of transforming growth factor-beta1, connective tissue growth factor, phosphorylated-SMAD2/3 and phosphorylated-ERK1/2 during mouse tooth development. J Mol Histol. 2017 Dec;48(5-6):347-355 |
1 | J:331948 Liu Z, Chen T, Bai D, Tian W, Chen Y, Smad7 Regulates Dental Epithelial Proliferation during Tooth Development. J Dent Res. 2019 Nov;98(12):1376-1385 |
1* | J:108109 Oxburgh L, Chu GC, Michael SK, Robertson EJ, TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development. 2004 Sep;131(18):4593-605 |
1 | J:134002 Pacheco MS, Reis AH, Aguiar DP, Lyons KM, Abreu JG, Dynamic analysis of the expression of the TGFbeta/SMAD2 pathway and CCN2/CTGF during early steps of tooth development. Cells Tissues Organs. 2008;187(3):199-210 |
1 | J:230021 Peng Y, Song L, Zhao M, Harmelink C, Debenedittis P, Cui X, Wang Q, Jiao K, Critical roles of miRNA-mediated regulation of TGFbeta signalling during mouse cardiogenesis. Cardiovasc Res. 2014 Jul 15;103(2):258-67 |
1 | J:264120 Rowan CJ, Li W, Martirosyan H, Erwood S, Hu D, Kim YK, Sheybani-Deloui S, Mulder J, Blake J, Chen L, Rosenblum ND, Hedgehog-GLI signaling in Foxd1-positive stromal cells promotes murine nephrogenesis via TGFbeta signaling. Development. 2018 Jul 9;145(13):dev159947 |
1* | J:189072 Spiller CM, Feng CW, Jackson A, Gillis AJ, Rolland AD, Looijenga LH, Koopman P, Bowles J, Endogenous Nodal signaling regulates germ cell potency during mammalian testis development. Development. 2012 Nov;139(22):4123-32 |
1 | J:334587 Wang L, Lin L, Qi H, Chen J, Grossfeld P, Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction. Circ Res. 2022 Aug 19;131(5):371-387 |
1 | J:223223 Wu Q, Fukuda K, Weinstein M, Graff JM, Saga Y, SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice. Development. 2015 Feb 1;142(3):575-86 |
1 | J:191052 Wu Q, Kanata K, Saba R, Deng CX, Hamada H, Saga Y, Nodal/activin signaling promotes male germ cell fate and suppresses female programming in somatic cells. Development. 2013 Jan;140(2):291-300 |
1 | J:218803 Yang G, Yuan G, Ye W, Cho KW, Chen Y, An atypical canonical bone morphogenetic protein (BMP) signaling pathway regulates Msh homeobox 1 (Msx1) expression during odontogenesis. J Biol Chem. 2014 Nov 7;289(45):31492-502 |
1 | J:217590 Yuan G, Yang G, Zheng Y, Zhu X, Chen Z, Zhang Z, Chen Y, The non-canonical BMP and Wnt/beta-catenin signaling pathways orchestrate early tooth development. Development. 2015 Jan 1;142(1):128-39 |
1 | J:257427 Yuan G, Zhan Y, Gou X, Chen Y, Yang G, TGF-beta signaling inhibits canonical BMP signaling pathway during palate development. Cell Tissue Res. 2018 Feb;371(2):283-291 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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